Phosphorylated dendronized poly(amido amine)s as protein analogues for directing hydroxylapatite biomineralization.

نویسندگان

  • Jianyu Xin
  • Tianchan Chen
  • Zaifu Lin
  • Ping Dong
  • Hong Tan
  • Jianshu Li
چکیده

Dendronized poly(amido amine)s (DPs) bearing tri-phosphate or bis-phosphonate peripheral groups are synthesized. These worm-like DPs can template the formation of BMSCs adhesive hydroxylapatite (HA) on the nano-scale, or self-assemble into mineral-collecting microfibers on the micro-scale, exhibiting similar functions of non-collagenous proteins (NCPs) in the natural biomineralization process of HA.

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عنوان ژورنال:
  • Chemical communications

دوره 50 49  شماره 

صفحات  -

تاریخ انتشار 2014